MicrobiologybioRxivPreprint
Acute induction of IFNα is responsible for the attenuation of the live measles vaccine
Jerome M. Edwards, Steve Yoon, Jacqueline Brockhurst…·Diane E. Griffin
This study identifies acute IFNα induction as the key mechanism by which the live measles vaccine is attenuated, revealing mutations in P/V/C and H genes responsible for this effect.