Scott A. Rankin

The paper shows that disruptions in endosomal trafficking of the Vangl-Celsr polarity complex cause congenital trachea-esophageal malformations in Xenopus, similar to human EA/TEF.

This study identifies Ventx2's role in regulating respiratory progenitor cell number and differentiation timing in Xenopus, with potential implications for human respiratory development.

This study identifies a gene regulatory network involving Tbx5, RA, Hedgehog, and Wnt signaling that coordinates cardiopulmonary development.

The paper identifies Sox17 and β-catenin interactions at enhancers that regulate endoderm gene expression and repression of mesectoderm fates during Xenopus gastrulation.

This paper identifies HH/Gli-dependent cellular mechanisms, including endosome-mediated remodeling and matrix degradation, essential for tracheoesophageal separation in mouse and Xenopus embryos.