Puf3 contributes to changes in mRNA solubility, translation elongation dynamics at rare arginine codons and loss of protein homeostasis in cells lacking Not4
Léna Audebert, George Edward Allen, Siyu Chen…·Martine A. Collart
Author
University of GenevaORCID 0000-0001-6955-1773Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
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Léna Audebert, George Edward Allen, Siyu Chen…·Martine A. Collart
Siyu Chen, George Edward Allen, Olesya O. Panasenko, Martine A. Collart
The paper identifies a mechanism called Mito-ENCay that limits MMF1 mRNA expression by targeting it to mitochondria and triggering quality control processes.
George Edward Allen, Benjamin Weiss, Olesya O. Panasenko…·Martine A. Collart
The paper shows that Not1 and Not4 oppositely regulate mRNA solubility, affecting co-translational dynamics in yeast.
Kaushik Bhattacharya, Samarpan Maiti, Szabolcs Zahorán…·Didier Picard
The paper shows that mammalian cells can maintain critical Hsp90 levels through translational reprogramming in response to stress, ensuring viability despite genetic loss of Hsp90 alleles.
Orsolya Németh‐Szatmári, Ádám Györkei, Dániel Varga…·Zoltán Villányi
The paper identifies proteins forming phase-separated ribosome-nascent chain complexes and shows they can resume translation after DNA damage.
George Edward Allen, Olesya O. Panasenko, Zoltán Villányi…·Martine A. Collart
The paper shows Not4 and Not5 regulate translation initiation and elongation differently, affecting codon-dependent ribosome behavior and translation efficiency.