Author

Roshani Sinha

University of California, San FranciscoORCID 0000-0001-6971-2725Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Benjamin J. LeschiD· 2 shared Eric SoupèneiD· 2 shared M. Kyle CromeriD· 2 shared Simon N. ChuiD· 2 shared Aadit P. ShahiD· 1 shared Anna BigasiD· 1 shared Antonio MaglittoiD· 1 shared Bertie GöttgensiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

Benjamin J. LeschORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 14, 2026

Combinatorial base editing couples disease correction with lineage amplification in hematopoietic stem and progenitor cells

Kun Jia, Eric Soupène, Roshani Sinha…·M. Kyle Cromer

This paper develops a combinatorial base editing strategy to enhance erythroid lineage amplification and disease correction in hematopoietic stem and progenitor cells.

DOI 10.64898/2026.04.13.718029

humanCRISPR screen

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Synthetic BiologybioRxivPreprintApr 12, 2024

Engineering inducible signaling receptors to enable erythropoietin-free erythropoiesis

Aadit P. Shah, Kiran R. Majeti, Freja K. Ekman…·M. Kyle Cromer

This paper develops small molecule-inducible EPO receptors to enable erythropoiesis without recombinant EPO, reducing costs and improving scalability of RBC manufacturing.

DOI 10.1101/2024.04.12.589260

humanexperimental assay

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Developmental BiologyThe EMBO JournalPeer-reviewedMar 9, 2020

Notch ligand Dll4 impairs cell recruitment into aortic clusters and limits hematopoietic stem cells

Cristina Porcheri, Ohad Golan, Fernando J. Calero‐Nieto…·Anna Bigas

The paper shows that Dll4 inhibits cell recruitment into aortic clusters, reducing hematopoietic stem cell formation.

DOI 10.15252/embj.2019104270

mouseexperimental assay

𝕏 PostBluesky