Single-cell characterization of the human immune landscape reveals dysfunction in monocyte-mediated cellular interactions in symptomatic malaria
Lorena Quatreville, Mathieu Adjemout, Charlyne Gard, Magali Torres, Camille Cohen, Brigitte Tumamo Fotso, Sandie Ménard, Abdel Yaya-Oye Akibou, Valérie Duplan-Eche, Anne-Laure Iscache, Martine Biarnes‐Pelicot, Balotin Fogang, Antoine Berry, Nicolas Blanchard, Lionel Spinelli, , Sandrine Marquet
The paper uses single-cell RNA sequencing to analyze immune cell interactions in asymptomatic and symptomatic malaria patients, finding reduced monocyte-T cell interactions and increased inflammation in symptomatic cases.
bioRxiv · Oct 20, 2026 · PreprintGenomics