Balotin Fogang

The paper uses single-cell RNA sequencing to analyze immune cell interactions in asymptomatic and symptomatic malaria patients, finding reduced monocyte-T cell interactions and increased inflammation in symptomatic cases.

The paper identifies large deletion variants in the PIMMS43 gene of Plasmodium falciparum and shows their geographic frequency variation and potential vector-specific selection.

The paper tracks malaria parasite lineages using de novo mutations in Plasmodium falciparum genomes from community infections in The Gambia, identifying recent mutations and transmission patterns.

This study identifies taurine as a host metabolite that inhibits malaria parasite cytoadhesion in asymptomatic infections, suggesting its potential as a therapeutic target.