Author

Jasper van Lopik

University of CambridgeORCID 0000-0001-6981-1504Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Benjamin Czech· 3 shared Gregory J. HannoniD· 3 shared Susanne BornelöviD· 3 shared Maria‐Anna TrapotsiiD· 2 shared Abdou AkkoucheiD· 1 shared Anna Sobieszek· 1 shared Azad AlizadaiD· 1 shared Émilie BrassetiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMolecular Biology

Benjamin Czech

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 14, 2024

FlaHMM: unistrand flamenco-like piRNA cluster prediction in Drosophila species using hidden Markov models

Maria‐Anna Trapotsi, Jasper van Lopik, Gregory J. Hannon…·Susanne Bornelöv

FlaHMM automates the identification of piRNA clusters in Drosophila species using hidden Markov models and genome sequence data alone.

DOI 10.1101/2024.05.14.592433

Drosophilastatistical model

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Molecular BiologybioRxivPreprintJan 11, 2024

A dual histone code specifies the binding of heterochromatin protein Rhino to a subset of piRNA source loci

Abdou Akkouche, Emma Kneuss, Susanne Bornelöv…·Gregory J. Hannon

The paper identifies a dual histone modification (H3K9me3 and H3K27me3) that specifies Rhino binding to a subset of piRNA source loci in Drosophila germ cells, independent of Kipferl.

11 citations

DrosophilaChIP-seq

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Molecular BiologyNature CommunicationsPeer-reviewedNov 13, 2023

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

Jasper van Lopik, Azad Alizada, Maria‐Anna Trapotsi…·Benjamin Czech

The paper identifies five additional flam-like piRNA clusters across 119 Drosophila species, showing conserved transposon silencing mechanisms in somatic ovarian cells.

40 citationstop 2%

Drosophilabulk RNA-seq

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