Azad Alizada

The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries

This study identifies Traffic jam as a master regulator of the somatic piRNA pathway in Drosophila ovaries, showing its role in controlling piRNA factors and the flamenco cluster.

Ovo is a master regulator of the piRNA pathway in animal ovarian germ cells

This study identifies Ovo as the master regulator of the germline piRNA pathway in Drosophila ovaries, showing its role in activating pathway components and binding to promoter motifs.

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

The paper identifies five additional flam-like piRNA clusters across 119 Drosophila species, showing conserved transposon silencing mechanisms in somatic ovarian cells.

Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-κB binding

The paper analyzes RELA-bound transposable elements across species to show their ancient and lineage-specific contributions to NF-κB binding and inflammation.