Author

Samuel K. Powell

Yale UniversityORCID 0000-0001-7002-2756Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Kristen BrennandiD· 3 shared Schahram AkbarianiD· 3 shared Callan P. O’SheaiD· 2 shared Kristina DobrindtiD· 2 shared Rahat Elahi· 2 shared Will LiaoiD· 2 shared Aditi ValadaiD· 1 shared Anina N. LundiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenomics

Kristen BrennandORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 17, 2023

Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes

Samuel K. Powell, Will Liao, Callan P. O’Shea…·Kristen Brennand

The paper maps 3D chromatin structures in neuronal subtypes and shows how schizophrenia risk loci reorganize during differentiation, linking regulatory loops to gene function.

2 citations

humanChIP-seq

𝕏 PostBluesky

NeuroscienceMolecular PsychiatryPeer-reviewedSep 7, 2021

Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk

Samuel K. Powell, Callan P. O’Shea, Kayla G. Townsley…·Kristen Brennand

This study develops a method to efficiently generate dopaminergic neurons from hiPSCs and shows they model psychiatric disease risk genes.

31 citations

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsComplex PsychiatryPeer-reviewedJan 1, 2020

Publicly available hiPSC lines with extreme polygenic risk scores for modeling schizophrenia

Kristina Dobrindt, Hanwen Zhang, Debamitra Das…·Kristen Brennand

The paper presents twelve hiPSC lines with extreme polygenic risk scores for schizophrenia, available for CRISPR-based functional studies.

36 citations

humanATAC-seq

𝕏 PostBluesky