Author
National Institutes of HealthORCID 0000-0001-7008-7509Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
James R. Barnacle, Nonzwakazi Bangani, Hubert Slawinski…·Robert John Wilkinson
This study identifies a hyper-inflammatory immune response in HIV-associated TB meningitis, marked by cytotoxic CD8 T cells, activated neutrophils, and type 1 interferon signaling.
Rosane M. B. Teles, Chaouki Benabdessalem, Jonathan Perrie…·Robert L. Modlin
This study identifies TREM2+ lipid-laden macrophages in alveolar TB pneumonia that support Mtb survival, contrasting with granulomas, and shows pharmacological reversal of this immunometabolic state.
Wei Lie Xiao, Andrew J. Sawyer, Siwei Mo…·Xinchun Chen
Xiao et al. reveal spatial segregation of immune cells in TB-lung tissue and link the microenvironmental dynamics to disease states of tuberculosis.
Paul J. Baker, Andrea C. Bohrer, Ehydel Castro…·Katrin D. Mayer-Barber
This study shows that pre-existing lung inflammation reduces SARS-CoV-2 replication by activating innate immune pathways, highlighting the role of the inflammatory microenvironment in controlling viral infection.