Author

James R. Barnacle

University of Cape TownORCID 0000-0003-1316-6205Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Angharad DavisiD· 1 shared Anne O’GarraiD· 1 shared Brian D. RobertsoniD· 1 shared Cari J. StekiD· 1 shared Christopher BarringtoniD· 1 shared Daniel L. BarberiD· 1 shared Fabrice BonnetiD· 1 shared Graeme MeintjesiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Angharad DavisORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintMar 23, 2026

Contribution of cytotoxic CD8 T cells, neutrophils and type 1 interferon signaling to hyperinflammation in HIV-associated TB meningitis

James R. Barnacle, Nonzwakazi Bangani, Hubert Slawinski…·Robert John Wilkinson

This study identifies a hyper-inflammatory immune response in HIV-associated TB meningitis, marked by cytotoxic CD8 T cells, activated neutrophils, and type 1 interferon signaling.

DOI 10.64898/2026.03.10.710544

humanbulk RNA-seq

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