Author

Sibusiso B. Maseko

University of LiègeORCID 0000-0001-7025-6106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:multiome· 1

Frequent Co-Authors

DAVID EDWIN HILLiD· 3 shared Jean‐Claude TwizereiD· 3 shared Marc VidaliD· 3 shared Michael A. CalderwoodiD· 3 shared Julien OlivetiD· 2 shared Kerstin SpirohniD· 2 shared Patricia CassonnetiD· 2 shared Tong HaoiD· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersSystems Biology

DAVID EDWIN HILLORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Systems BiologyMolecular Systems BiologyPeer-reviewedMar 11, 2024

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Philipp Trepte, Christopher Secker, Julien Olivet…·Erich E. Wanker

The paper presents an AI-guided pipeline for PPI drug discovery, identifying a SARS-CoV-2 inhibitor by combining experimental assays, machine learning, and virtual screening.

35 citationstop 2%

protein structuremachine learning (classical)

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Systems BiologyNature BiotechnologyPeer-reviewedOct 10, 2022

A map of binary SARS-CoV-2 protein interactions implicates host immune regulation and ubiquitination

Dae‐Kyum Kim, Benjamin Weller, Chung‐Wen Lin…·Pascal Falter‐Braun

The paper maps binary SARS-CoV-2 protein interactions with host proteins, identifying key processes like immune signaling and ubiquitination, and suggests therapeutic targets.

66 citationstop 2%

humanproteomics

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Systems BiologyPLoS PathogensPeer-reviewedSep 20, 2021

The viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape

Charlotte Vandermeulen, Tina M. O’Grady, Jérôme Wayet…·Jean‐Claude Twizere

This study shows that Tax and HBZ, viral oncoproteins, alter mRNA splicing in T-cells by interacting with spliceosome components, leading to changes in cancer-related genes.

36 citations

humanmultiome

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