Author
Centre National de la Recherche ScientifiqueORCID 0000-0002-4809-470XUnclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Philipp Trepte, Christopher Secker, Julien Olivet…·Erich E. Wanker
The paper presents an AI-guided pipeline for PPI drug discovery, identifying a SARS-CoV-2 inhibitor by combining experimental assays, machine learning, and virtual screening.
Dae‐Kyum Kim, Benjamin Weller, Chung‐Wen Lin…·Pascal Falter‐Braun
The paper maps binary SARS-CoV-2 protein interactions with host proteins, identifying key processes like immune signaling and ubiquitination, and suggests therapeutic targets.
Philipp Trepte, Christopher Secker, Soon Gang Choi…·Erich E. Wanker
The paper presents a framework combining two high-throughput interaction assays to distinguish direct from indirect protein interactions in complexes.
Payman Samavarchi‐Tehrani, Hala S. Abdouni, James D.R. Knight…·Anne‐Claude Gingras
Proximity-dependent biotinylation of 27 SARS-CoV-2 proteins in A549 cells maps 7810 virus-host proximity interactions across 2242 host proteins, including membrane-associated partners missed by affinity purification.
Estelle M. N. Laurent, Yorgos Sofianatos, Anastassia V. Komarova…·Étienne Coyaud
Proximity-dependent biotinylation (BioID) of 28 SARS-CoV-2 proteins in human cells maps 5,415 proximal interactions with 2,128 host targets across basal and poly(I:C) conditions.
Soon Gang Choi, Julien Olivet, Patricia Cassonnet…·Yves Jacob
The paper introduces an assayome concept to optimize binary interactome mapping by combining multiple assay versions, achieving high true positive detection with minimal assays.