Systems BiologyJournal of Cell SciencePeer-reviewed
AKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture
Dongqing Zheng, Jonathan H. Sussman, Matthew P. Jeon…·Nicholas Alexander Graham
The paper shows that AKT, but not MYC, causes cell death in oxidative conditions by increasing reactive oxygen species, revealing a metabolic vulnerability in cancer cells.
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