Author

Jae Kyo Yi

Dana-Farber Cancer InstituteORCID 0000-0001-7053-601XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander SpektoriD· 1 shared Jisun LeeiD· 1 shared Leslie M. ShawiD· 1 shared Pilhan KimiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Alexander SpektorORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintOct 10, 2025

Synergistic targeting of MCL1 and caspases for enhanced anti-tumor immunity in breast cancer.

Jae Kyo Yi, Jisun Lee, Pilhan Kim…·Alexander Spektor

This study shows that combining MCL1 and caspase inhibition enhances anti-tumor immunity in breast cancer by activating the cGAS-STING pathway and remodeling the tumor microenvironment.

DOI 10.1101/2025.10.10.681458

mousebulk RNA-seq

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