Georgy Koentges

The paper identifies a Cx26+ neural crest lineage that emerges in mid-life and mediates enhanced CO2 responses in the brainstem, impacting breathing and metabolism.

The paper reveals that dermal bone growth involves cellular invasion and intercalary biomineralization, challenging the traditional model of matrix apposition by superficial osteoblasts.

The paper identifies a common lineage origin of endothelial cells and osteoblasts and reveals de novo vasculogenesis as a key mechanism in dermal bone remodeling in vertebrates.

This study identifies Hox4/5 and Hox6/7 genes' roles in forelimb positioning through loss- and gain-of-function experiments in chick embryos, showing Hox4/5 provide permissive cues and Hox6/7 determine limb position.