Cancer BiologyNature CommunicationsPeer-reviewed
Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity
Nicolas Pasquier, Meri Pelkonen, Elise Carraz-Billat…·Johanna Ivaska
The paper identifies a signaling axis involving SorLA, integrin, and HER2/HER3 that regulates apicobasal polarity in mucinous colorectal adenocarcinoma and shows its therapeutic relevance.
DOI 10.1038/s41467-026-75127-0