Author

Irina Belaya

University of Eastern FinlandORCID 0000-0001-7594-0679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Katja M. KannineniD· 3 shared Tarja MalmiD· 3 shared Henna Konttinen· 2 shared Jari KoıstınahoiD· 2 shared Liudmila SavelevaiD· 2 shared Nikita MikhailoviD· 2 shared Paula KorhoneniD· 2 shared Rashid A. GiniatulliniD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersNeuroscience

Katja M. KanninenORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJul 4, 2026

Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity

Nicolas Pasquier, Meri Pelkonen, Elise Carraz-Billat…·Johanna Ivaska

The paper identifies a signaling axis involving SorLA, integrin, and HER2/HER3 that regulates apicobasal polarity in mucinous colorectal adenocarcinoma and shows its therapeutic relevance.

DOI 10.1038/s41467-026-75127-0

humanbulk RNA-seq

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NeurosciencebioRxivPreprintMar 18, 2022

Microglial amyloid beta clearance is driven by PIEZO1 channels

Henna Konttinen, Valeria Sitnikova, Yevheniia Ishchenko…·Tarja Malm

This study shows that activating PIEZO1 channels in microglia improves amyloid beta clearance in AD models by enhancing survival, phagocytosis, and lysosomal activity.

3 citations

humanmouse

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NeuroscienceNeuroToxicologyPeer-reviewedJan 6, 2022

Subacute Inhalation of Ultrafine Particulate Matter Triggers Inflammation Without Altering Amyloid Beta Load in 5xFAD mice.

Liudmila Saveleva, Petra Vartiainen, Veronika Górová…·Katja M. Kanninen

16 citations

mouseexperimental assay

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NeurosciencebioRxivPreprintSep 15, 2021

Alzheimer's disease alters astrocytic functions related to neuronal support andtranscellular internalization of mitochondria

Riikka Lampinen, Irina Belaya, Liudmila Saveleva…·Katja M. Kanninen

This study shows increased mitochondrial internalization and degradation by astrocytes in Alzheimer's disease, suggesting altered neuron-supporting functions and involvement of S100a4 and Ambra1.

1 citation

mousehuman

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