William Paul Duprex

This paper establishes two mouse models of Oropouche virus-induced hepatitis, showing that Type I interferons control disease severity and that contemporary isolates are less pathogenic than historical strains.

This study characterizes Oropouche orthobunyavirus replication in neural cells and brain slices, showing cytokine production and providing a model for studying viral neuropathogenesis.

This study identifies acute IFNα induction as the key mechanism by which the live measles vaccine is attenuated, revealing mutations in P/V/C and H genes responsible for this effect.

This study shows that deleting the Envelope gene in SARS-CoV-2 increases cell surface Spike protein and cell-to-cell transmission, reducing neutralizing antibody inhibition.

The paper identifies six divergent morbilliviruses in Neotropical bats and NHPs, showing their role in evolutionary diversification and potential zoonotic risk.

This study shows that pre-existing H1N1 immunity protects ferrets from severe disease caused by bovine H5N1 influenza virus.