Succinate and its carrier Sfc1 mediate metabolic control of mitochondrial protein import by the TIM23 translocase
Koyeli Das, Rituparna Samanta, Tamar Ziv, Johannes M. Herrmann, Bella Kalderon, Ophry Pines
The paper shows that succinate and its carrier Sfc1 regulate mitochondrial protein import via interaction with Tim23, affecting enzyme localization between mitochondria and cytosol.
Cell Reports · Aug 1, 2026Peer-reviewedCell Biology