Rituparna Samanta

Succinate and its carrier Sfc1 mediate metabolic control of mitochondrial protein import by the TIM23 translocase

The paper shows that succinate and its carrier Sfc1 regulate mitochondrial protein import via interaction with Tim23, affecting enzyme localization between mitochondria and cytosol.

Advancing membrane-associated protein docking with improved sampling and scoring in Rosetta

This paper introduces Rosetta-MPDock, a membrane protein docking method that improves prediction accuracy by capturing conformational changes and integrating AlphaFold2-multimer, achieving better success rates in predicting membrane protein complex structures.

ProteinMPNN Recovers Complex Sequence Properties of Transmembrane β-Barrels

This study benchmarks ProteinMPNN for designing transmembrane β-barrel proteins, showing it outperforms Franklin2023 with refined inputs and generates sequences suitable for experimental validation.

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

The paper presents a framework for ensuring reproducibility in bio-macromolecular modeling through automated benchmarks and a test server, demonstrating its utility for Rosetta and other tools.