Vinodh Pillai

The paper identifies P2RX5 as a new B-cell surface marker and multi-lineage immunotherapy target, showing its expression in B-cell malignancies and T-cell leukemia, and demonstrating the efficacy of P2RX5-directed therapies.

This paper develops anti-CD2 CAR T-cells that overcome fratricide and improve efficacy by incorporating a PD-1:CD2 switch receptor to restore CD2 signaling.

This study maps the spatial and single-cell landscape of Castleman Disease, identifying key stromal cell types and cytokine pathways involved in disease pathology.

This study uses RNA-seq to identify differentially expressed genes and pathways in seven non-neoplastic lymphadenitis entities to find potential molecular diagnostic markers.

This study maps human bone marrow niches using single-cell transcriptomics and proteomic imaging, identifying distinct cellular environments and their roles in hematopoiesis and AML.