Author

Afshin Varzavand

University of IowaORCID 0000-0001-7137-6580Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam J. DupuyiD· 1 shared Adeline A. Hawkins· 1 shared Christopher S. StippiD· 1 shared Elizabeth C. HannaniD· 1 shared Faith A. Bibeau· 1 shared Jesse D. RiordaniD· 1 shared Jonathan A. PachteriD· 1 shared Madison C. Jilek· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adam J. DupuyORCID

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1 paper

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedOct 18, 2025

A critical role of FAK signaling in Rac1-driven melanoma cell resistance to MAPK pathway inhibition

Jesse D. Riordan, Teagan A. Nathanson, Afshin Varzavand…·Christopher S. Stipp

This study identifies FAK signaling as a critical target for overcoming Rac1-driven MAPK resistance in melanoma and shows that combining RAF/MEK and FAK inhibitors is effective.

7 citations

humanproteomics

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