Rimma Levina

This paper uses CRISPR-mediated conditional mutagenesis to show BMP/GDF signaling restricts postnatal bone overgrowth by regulating both periosteal and endosteal osteoblasts.

This study shows that meiotic Cas9 expression can mediate genotype conversion in both male and female mouse germlines, but low Cas9 levels limit efficiency.

The paper identifies three classes of enhancers regulated by Bicoid and Orthodenticle in Drosophila embryos, revealing a feed-forward relay mechanism that coordinates gene expression timing.