A genotoxin associated with colorectal cancer linked to gut dysbiosis in children with cystic fibrosis
Kaitlyn E. Barrack, Sarvesh V. Surve, Antonia Karine Silva Bezerra, Caitlin E. Murphy, Shannon M. Soucy, Miguel A. Aguilar Ramos, Rebecca A. Valls, Rebekah D. Ruff, Emily P. Balskus, Julie L. Sanville, Juliette C. Madan, George A. O’Toole
This study investigates microbial dysbiosis in children with cystic fibrosis, identifying glycerol as a driver of altered microbial competition and linking colibactin production to increased colorectal cancer risk.
Journal of Bacteriology · Jun 9, 2026Peer-reviewedMicrobiology