Fluoxetine improves behavioural deficits induced by chronic alcohol addiction by alleviating RNA editing of 5-HT2C receptors in astrocytes
Zexiong Li, Yan Lü, Shanshan Liang, Shuai Li, Beina Chen, Manman Zhang, Maosheng Xia, Dawei Guan, Alexei Verkhratsky, Baoman Li
This study shows that fluoxetine alleviates alcohol addiction by reducing RNA editing of 5-HT2C receptors in astrocytes, thereby increasing ATP release and improving behavioral symptoms.
Neurochemistry International · Jan 20, 2020Peer-reviewedNeuroscience