Author

Dawei Guan

China Medical UniversityORCID 0000-0002-9439-6557Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alexei VerkhratskyiD· 3 shared Baoman LiiD· 3 shared Beina Chen· 3 shared Maosheng XiaiD· 3 shared Shanshan LiangiD· 3 shared Chengyi Dong· 2 shared Manman ZhangiD· 2 shared Shuai LiiD· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersNeuroscience

Alexei VerkhratskyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceFunctionPeer-reviewedJan 12, 2021

Iatrogenic Iron Promotes Neurodegeneration and Activates Self-protection of Neural Cells against Exogenous Iron Attacks

Maosheng Xia, Shanshan Liang, Shuai Li…·Baoman Li

This study investigates the impact of iron from metal implants on neural cells, finding that iron accumulation affects neuronal function and may increase neurodegeneration risk.

25 citations

humanexperimental assay

𝕏 PostBluesky

NeuroscienceNeuroscience BulletinPeer-reviewedJun 6, 2020

Sleep deprivation selectively down-regulates astrocytic 5-HT2B receptors and triggers depressive-like behaviors via stimulating P2X7 receptors

Maosheng Xia, Zexiong Li, Shuai Li…·Baoman Li

This study shows chronic sleep deprivation reduces astrocytic 5-HT2B receptors via P2X7 receptors, leading to depressive-like behaviors through increased arachidonic acid and PGE2 release.

55 citationstop 3%

mousestatistical model

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NeuroscienceNeurochemistry InternationalPeer-reviewedJan 20, 2020

Fluoxetine improves behavioural deficits induced by chronic alcohol addiction by alleviating RNA editing of 5-HT2C receptors in astrocytes

Zexiong Li, Yan Lü, Shanshan Liang…·Baoman Li

This study shows that fluoxetine alleviates alcohol addiction by reducing RNA editing of 5-HT2C receptors in astrocytes, thereby increasing ATP release and improving behavioral symptoms.

21 citations

mousebulk RNA-seq

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