Author

Zexiong Li

China Medical UniversityORCID 0000-0002-5515-3368Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alexei VerkhratskyiD· 3 shared Baoman LiiD· 3 shared Beina Chen· 3 shared Maosheng XiaiD· 3 shared Shanshan LiangiD· 3 shared Chengyi Dong· 2 shared Dawei GuaniD· 2 shared Shuai LiiD· 2 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersNeuroscience

Alexei VerkhratskyORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 6, 2020

Astrocytes express DMT1 and transferrin receptors, which transport iron thus activating Ca2+ signalling: possible role in neuroprotection against iron overload?

Maosheng Xia, Wenzheng Guan, Ming Hua Ji…·Baoman Li

This study investigates how iron ions affect calcium signaling in astrocytes through DMT1 and TFR, revealing mechanisms of neuroprotection against iron overload.

1 citation

statistical modelexperimental assay

𝕏 PostBluesky

NeuroscienceNeuroscience BulletinPeer-reviewedJun 6, 2020

Sleep deprivation selectively down-regulates astrocytic 5-HT2B receptors and triggers depressive-like behaviors via stimulating P2X7 receptors

Maosheng Xia, Zexiong Li, Shuai Li…·Baoman Li

This study shows chronic sleep deprivation reduces astrocytic 5-HT2B receptors via P2X7 receptors, leading to depressive-like behaviors through increased arachidonic acid and PGE2 release.

55 citationstop 3%

mousestatistical model

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NeuroscienceNeurochemistry InternationalPeer-reviewedJan 20, 2020

Fluoxetine improves behavioural deficits induced by chronic alcohol addiction by alleviating RNA editing of 5-HT2C receptors in astrocytes

Zexiong Li, Yan Lü, Shanshan Liang…·Baoman Li

This study shows that fluoxetine alleviates alcohol addiction by reducing RNA editing of 5-HT2C receptors in astrocytes, thereby increasing ATP release and improving behavioral symptoms.

21 citations

mousebulk RNA-seq

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