Sebastian Shaw

The paper identifies an RNA-binding protein essential for female gamete development and sporozoite infectivity in Cryptosporidium by analyzing single-cell data and conducting conditional ablation experiments.

The paper identifies a multi-kingdom microbial consortium that normalizes immune responses in laboratory mice, altering cancer outcomes and CAR T cell therapy responses.

The paper identifies genomic heterogeneity at the NDH2 locus in Cryptosporidium species that contributes to clofazimine resistance through adaptive recombination.

The paper identifies genomic loci associated with virulence in Cryptosporidium parvum by analyzing genetic crosses and whole-genome sequencing in mice.