Jikui Song

This study reports the structure of the AMT complex bound to OCR protein, revealing its substrate binding mechanism and conformational changes during 6mA methylation.

The paper identifies METTL7A as a factor that promotes TKI resistance and oncogene amplification in lung cancer by remodeling chromatin structure before copy number gains.

This study investigates how CMT2 and CMT3 diverge in substrate specificity and protein stability, revealing evolutionary mechanisms of DNA methylation in plants.

The paper demonstrates that DNA N6-adenine methylation (6mA) is transmitted semi-conservatively in Tetrahymena thermophila, with AMT1-dependent maintenance and AMT1-independent de novo methylation mechanisms.

This study identifies the RFTS domain of DNMT1 as a reader for H3K9me3/H3Ub, showing its role in DNA methylation maintenance and genomic stability.

This study characterizes the structure-function differences between DNMT3A and DNMT3B, revealing distinct mechanisms of de novo DNA methylation and their implications in epigenomic alterations.