Sajjad Khani

This study identifies the Nfe2l1-Atf3 pathway as a regulator of cholesterol-induced adipocyte inflammation and insulin resistance in both human and mouse models.

The paper benchmarks ONT long-read sequencing against Illumina short-read sequencing in cold-activated BAT, finding ONT superior for transcriptome reassembly but less powerful for differential expression analysis.

The paper investigates the role of the adipose tissue-specific lncRNA Gm15551 in BAT activation through transcriptional profiling and phenotyping, finding no significant effect on adipocyte function.

This study identifies AATBC as a human-specific lncRNA that regulates adipocyte plasticity and mitochondrial function, linking it to metabolic health.

This study identifies HAND2 as an obesity-linked adipogenic transcription factor regulated by glucocorticoids, showing its role in adipocyte differentiation and its correlation with BMI in humans.