Divalent cations govern the activity of coronavirus nsp15
Xionglue Wang, Jie Li, Zhichao Liu…·Bin Zhu
The paper shows that Co2+ and Ni2+ activate coronavirus nsp15, while Zn2+ inhibits it, and explains the structural basis for this activity.
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University of GeorgiaORCID 0000-0003-3902-642XUnclaimed ORCID profile · follow to get notified of new preprints
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5 papers
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Xionglue Wang, Jie Li, Zhichao Liu…·Bin Zhu
The paper shows that Co2+ and Ni2+ activate coronavirus nsp15, while Zn2+ inhibits it, and explains the structural basis for this activity.
Jie Li, Lucas P. Wachsmuth, Shiyun Xiao…·Nancy Ruth Manley
This study shows Foxn1 overexpression in TECs promotes proliferation and differentiation but does not prevent aging-related thymic involution.
Zhaotong Cong, Fulai Zhou, Chao Zhang…·Ming‐Wei Wang
The paper identifies a splice variant of the GHRHR receptor that mediates constitutive signal bias towards β-arrestin recruitment, impacting downstream signaling pathways in prostate cancer cells.
Jie Li, Julie Gordon, Edward L.Y. Chen…·Nancy Ruth Manley
This study shows Notch1 signaling is essential for specifying and expanding the medullary thymic epithelial cell (mTEC) progenitor pool during mouse fetal development.