James T. Grist

This study uses multimodal metabolic analysis to detect early metabolic changes in acute neuroinflammation, showing reduced pyruvate metabolism and ongoing inflammation without structural MRI changes.

This study investigates how elevated serum lactate affects cerebral perfusion and metabolism in anesthetized rodents using hyperpolarized 13C MRI, finding significant changes in perfusion and lactate:pyruvate ratios but not bicarbonate:pyruvate ratios.

This paper evaluates the effects of ninerafaxstat on cardiac energetics and function in patients with cardio-metabolic syndromes using hyperpolarized MR and metabolomics.