Author

Hei‐Yong G. Lo

University of Colorado AnschutzORCID 0000-0001-7253-6873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:benchmark study· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:software / tool· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

J. Matthew TaliaferroiD· 2 shared Raeann GoeringiD· 2 shared Robert C. SpitaleiD· 2 shared Abraham MartineziD· 1 shared Agnese KocereiD· 1 shared Angeles B. RiberaiD· 1 shared Bruce H. MandtiD· 1 shared Chad G. PearsoniD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

J. Matthew TaliaferroORCID

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3 papers

Recent·Most cited

TO BE OR NOT TO BE A PI: ADVICE FOR TRAINEES IN THE BIOMEDICAL/BASIC SCIENCES

Hei‐Yong G. Lo, Lily L. Nguyen, KRISTINE M. SIKORA, Bruce H. Mandt, Angeles B. Ribera

The paper surveys PIs to provide insights into the PI career path, revealing mixed attitudes and the importance of luck alongside scientific skills.

bioRxiv · Dec 9, 2025 · PreprintScientific Communication & Education

Quantification of subcellular RNA localization through direct detection of RNA oxidation

Hei‐Yong G. Lo, Raeann Goering, Agnese Kocere, Joelle Lo, Megan C Pockalny, Laura K. White, Haydee Ramirez, Abraham Martinez, Seth Jacobson, Robert C. Spitale, Chad G. Pearson, Marino J. E. Resendiz, Christian Mosimann, J. Matthew Taliaferro

This paper introduces OINC-seq, a method to quantify subcellular RNA localization through direct oxidation detection, and demonstrates its application in various cellular compartments and live zebrafish.

Nucleic Acids Research · Feb 12, 2025Peer-reviewedMolecular Biology

Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq

Krysta L. Engel, Hei‐Yong G. Lo, Raeann Goering, Ying Li, Robert C. Spitale, J. Matthew Taliaferro

This study introduces Halo-seq, a method for quantifying subcellular RNA populations, and finds that AU-rich elements are enriched in the nucleus and their export depends on HuR.

Nucleic Acids Research · Nov 16, 2021Peer-reviewedMolecular Biology