Laura K. White

This study shows that loss of polr1c in zebrafish causes reduced myelination and craniofacial defects, with Tp53 pathway activation but no apoptosis in oligodendrocyte precursors.

This study shows that cfDNA can map telomere chromatin structure, revealing age-related and disease-specific changes in telomeric footprints and gene signatures.

This paper introduces a method to simultaneously measure tRNA sequence, modification, and aminoacylation using nanopore sequencing and machine learning.

This paper introduces OINC-seq, a method to quantify subcellular RNA localization through direct oxidation detection, and demonstrates its application in various cellular compartments and live zebrafish.

This study demonstrates the use of updated nanopore sequencing to characterize 43 RNA modifications in tRNAs, including mitochondrial and viral tRNAs, and provides best practices for future research.

The paper identifies unique nanopore sequencing signals from 2'-phosphorylated RNAs, enabling detection of RNA repair events in yeast.