Author

Tomohisa Okamura

The University of TokyoORCID 0000-0001-7257-5557Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Hirofumi ShodaiD· 2 shared Kazuhiko YamamotoiD· 2 shared Kazuyoshi IshigakiiD· 2 shared Keishi FujioiD· 2 shared Mineto OtaiD· 2 shared Takahiro ItamiyaiD· 2 shared Akio MorinobuiD· 1 shared Aya Nishiwaki· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

Hirofumi ShodaORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 29, 2026

An APOC1+ inflammatory CAF-like state drives a senescent, treatment-resistant niche in rheumatoid arthritis

Risa Yoshihara, Sotaro Nakajima, Reo Yamazato…·Keishi Fujio

The paper identifies a treatment-resistant fibroblast state in RA synovitis that drives chronic inflammation through senescence-associated mechanisms and highlights therapeutic targets beyond cytokine inhibition.

DOI 10.64898/2026.04.17.718831

humanscRNA-seq

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintJan 12, 2022

Cell-type-specific transcriptome architecture underlying the establishment and exacerbation of systemic lupus erythematosus

Masahiro Nakano, Mineto Ota, Yusuke Takeshima…·Keishi Fujio

This study identifies cell-type-specific transcriptomic signatures associated with SLE disease establishment and exacerbation, highlighting their clinical relevance and potential limitations in capturing genetic risk factors.

DOI 10.1101/2022.01.12.22269137

humanbulk RNA-seq

𝕏 PostBluesky