Author

Akio Morinobu

Kyoto UniversityORCID 0000-0002-4672-638XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Haruka TsuchiyaiD· 1 shared Hirofumi ShodaiD· 1 shared Ikuko Naka· 1 shared Ikuo TakazawaiD· 1 shared Jun SaegusaiD· 1 shared Kazuhiko YamamotoiD· 1 shared Kazuyoshi IshigakiiD· 1 shared Keishi FujioiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Haruka TsuchiyaORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 29, 2026

An APOC1+ inflammatory CAF-like state drives a senescent, treatment-resistant niche in rheumatoid arthritis

Risa Yoshihara, Sotaro Nakajima, Reo Yamazato…·Keishi Fujio

The paper identifies a treatment-resistant fibroblast state in RA synovitis that drives chronic inflammation through senescence-associated mechanisms and highlights therapeutic targets beyond cytokine inhibition.

DOI 10.64898/2026.04.17.718831

humanscRNA-seq

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ImmunologybioRxivPreprintJun 25, 2025

Dual inhibition of glutaminolysis and autophagy suppresses proliferation of Rheumatoid arthritis fibroblast-like synoviocytes and mitigates arthritis in SKG mice

Ikuko Naka, Sho Sendo, T. Okano…·Jun Saegusa

This study shows that inhibiting both glutaminolysis and autophagy reduces RA-FLS proliferation and arthritis in SKG mice.

DOI 10.1101/2025.06.25.661649

mousebulk RNA-seq

𝕏 PostBluesky