Pieter J. Hoekstra

This study compares thalamic nucleus volumes across multiple psychiatric and neurological disorders using MRI, finding significant volume reductions in specific regions associated with different conditions.

This study identifies six genome-wide significant risk loci for tic disorders and links genetic risk to specific brain cell types and circuits.

This study investigates brain age differences in youth with conduct disorder compared to controls, finding accelerated brain maturation in those with adolescence-onset CD.

The paper investigates how polygenic risk scores and environmental factors contribute to tic occurrence in a cohort study, finding additive and mediated effects.

The paper analyzes cortical thickness trajectories in 17,075 individuals to show peak thickness in childhood, steep decline in early adulthood, and slower decline later, with notable exceptions and significant inter-individual variability.

This study uses machine learning to show that structural brain anomalies in ADHD are similar in children and adults, supporting continuity of the disorder's pathophysiology.

The paper analyzes sex differences in brain structure variability across the lifespan using a large dataset, finding greater male variability in subcortical volumes, cortical surface area, and thickness in most regions.

This study analyzes subcortical volume changes across the lifespan using MRI data from 18,605 individuals, finding age-related declines in some structures and increases in others.

Cross-disorder meta-analysis of eight psychiatric GWAS (232,964 cases, 494,162 controls) reports 109 loci shared by two or more disorders and three groups of correlated disorders.