Author
Tufts UniversityORCID 0000-0001-7261-9214Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Taylor Stewart, Benjamin E. Wolfe, Stephen M. Fuchs
This study identifies the role of the polyasparagine domain in Azf1p, showing it influences gene regulation related to carbon metabolism but is not essential for localization or prion formation.
Nealia C. M. House, Erica J. Polleys, Ishtiaque Quasem…·Catherine H. Freudenreich
The paper investigates the role of H2A subtypes in CAG/CTG repeat instability in yeast, finding H2A.1 protects against expansion and its phosphorylation at Thr126 is critical for repair fidelity.
Taylor Stewart, Alexandra E. Exner, Paras Patnaik, Stephen M. Fuchs
The paper investigates the mechanism of CTD contraction in S. cerevisiae, finding that it involves Rad5p-dependent template switching and G-quadruplex formation.
Michael Babokhov, Bradley I. Reinfeld, Kevin Hackbarth…·Stephen M. Fuchs
The paper identifies that tandem repeat variation in budding yeast is strongly correlated with intrinsically disordered regions and may modulate protein function.
Michael Babokhov, Mubeen Mosaheb, Richard W. Baker, Stephen M. Fuchs
This study shows that different positions of identical CTD repeats in budding yeast RNAPII have distinct functional roles, identified through mutational analysis and phenotypic measurements.