GeneticsNature CommunicationsPeer-reviewed
Structure-forming CAG/CTG repeats interfere with gap repair to cause repeat expansions and chromosome breaks
Erica J. Polleys, Isabella S. Del Priore, Marjorie de la Rosa Mejia…·Catherine H. Freudenreich
The paper shows that CAG/CTG repeats in ssDNA gaps influence repair kinetics, leading to repeat expansions or contractions and chromosome breaks.
22 citations