Chung‐I Wu

This study identifies Cancer Driving Nucleotides (CDNs) across cancer types and patients, finding that most remain unidentified and highlights the need for larger sample sizes to improve detection.

This study develops a theory to identify Cancer Driving Nucleotides (CDNs) by analyzing mutation recurrence across large cancer datasets, finding that mutations recurring at least three times are likely CDNs.

The paper integrates the Wright-Fisher and Haldane models to resolve paradoxes in genetic drift by defining it through variance in transmission success rather than population size.

This study shows that reduced miRNA levels in Drosophila lead to developmental instability and reduced longevity, highlighting miRNAs' role in stabilizing gene regulatory networks against weak environmental perturbations.

The paper studies chromosomal evolution in cancer cell lines, finding that cells lose sex chromosomes and gain autosomes, leading to a 2:3 X:A ratio that may enhance fitness.