Aline Le Roy

This study benchmarks DSF across labs, showing variability in thermal stability parameters due to instruments, workflows, and fluorescence readouts, with harmonization and centralized analysis improving consistency.

The paper determines the structure of Llp and analyzes the FhuA:Llp complex to understand superinfection exclusion in bacteriophage T5.

The paper identifies a lipid-binding site in the dimeric E. coli DedA protein YqjA through structural modeling and functional assays, showing lipid binding enhances thermal stability and is essential for function.

This study reveals that SpoIVA forms track-like polymers during bacterial spore development, with dimerization and ATPase activity playing distinct roles in its assembly and function.

This study uses sedimentation velocity analytical ultracentrifugation to investigate COSAN micelle aggregation and its effect on protein assembly, confirming a critical micelle concentration and revealing discrete aggregation states.