BioengineeringbioRxivPreprint
In vivo generation of chimeric antigen receptor T cells using optimally retargeted and functionalized lentiviral vectors with reduced immune clearance
Kepler S. Mears, Kyrellos E. Ibrahim, Peter M. Allen…·Robert T. Manguso
This study develops lentiviral vectors with improved specificity and reduced immune clearance for in vivo CAR T cell generation, showing efficacy in a preclinical model.
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