Author

Chloe Ding

Boston UniversityORCID 0000-0001-7277-5081Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Wilson W. WongiD· 2 shared Benjamin H. WeinbergiD· 1 shared Cristina Tous· 1 shared Declan G. BatesiD· 1 shared Jack E. Bowyer· 1 shared Jaehoon ChoiiD· 1 shared Jingyao CheniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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2 shared papersSynthetic Biology

Wilson W. WongORCID

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2 papers

Recent·Most cited

Synthetic BiologyNature CommunicationsPeer-reviewedFeb 21, 2024

Orthogonal inducible control of Cas13 circuits enables programmable RNA regulation in mammalian cells

Chloe Ding, Cristina Tous, Jaehoon Choi…·Wilson W. Wong

This paper introduces CRISTAL, a platform for programmable RNA regulation using inducible Cas13 circuits, enabling precise temporal control and multiplexed gene regulation in mammalian cells.

27 citationstop 5%

humanmouse

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Synthetic BiologyPLoS Computational BiologyPeer-reviewedDec 18, 2020

A mechanistic model of the BLADE platform predicts performance characteristics of 256 different synthetic DNA recombination circuits

Jack E. Bowyer, Chloe Ding, Benjamin H. Weinberg…·Declan G. Bates

The paper develops a mechanistic model of the BLADE platform to predict performance of 256 synthetic DNA recombination circuits, showing good agreement with experimental data and identifying factors affecting circuit performance.

7 citations

DNA methylationstatistical model

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