Author

Jaehoon Choi

Boston UniversityORCID 0009-0007-8938-1821Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Wilson W. WongiD· 2 shared Chloe DingiD· 1 shared Christopher WuiD· 1 shared Cristina Tous· 1 shared Devin MuthaiD· 1 shared Jingyao CheniD· 1 shared Mark W. GrinstaffiD· 1 shared Neil J. GanemiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBioengineering

Wilson W. WongORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintMar 21, 2026

Self-amplifying RNA-based CAR T cell therapy with enhanced duration and multi-genic logic functions

Yuyang Gu, Jaehoon Choi, Devin Mutha…·Wilson W. Wong

This paper develops a self-amplifying RNA platform for CAR T cells that improves durability and enables multi-genic logic functions, showing superior tumor suppression in a leukemia model.

2 citations

mouseexperimental assay

𝕏 PostBluesky

Synthetic BiologyNature CommunicationsPeer-reviewedFeb 21, 2024

Orthogonal inducible control of Cas13 circuits enables programmable RNA regulation in mammalian cells

Chloe Ding, Cristina Tous, Jaehoon Choi…·Wilson W. Wong

This paper introduces CRISTAL, a platform for programmable RNA regulation using inducible Cas13 circuits, enabling precise temporal control and multiplexed gene regulation in mammalian cells.

27 citationstop 5%

humanmouse

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