Brandon Milholland

This study identifies miR-142-3p as a regulator of human longevity by modulating the insulin/IGF-1 signaling pathway in B-cells and mice.

The paper proposes a mixture model for human lifetimes that accounts for finite individual lifespans and collectively unbounded lifetimes, predicting some individuals will live past 120 but few will reach 125.

The paper constructs a population model of human lifetimes with a finite upper bound on longevity, differing from claims of unbounded human lifetimes.