A new Persister Enrichment Model in Mycobacterium tuberculosis links multidrug persistence to drug sequencing and maltokinase-dependent carbon distribution.
Michael W. Shultis, Claire V. Mulholland, Jinhua Cui, M Chen, Samantha Johnson, Christopher R. Hiner, Michael Berney
This paper introduces a Persister Enrichment Model (PEM) to study multidrug persistence in M. tuberculosis, showing that drug sequencing and maltokinase-dependent carbon distribution influence antibiotic tolerance.
bioRxiv · May 29, 2026 · PreprintMicrobiology