Author

Le Xiao

Harvard UniversityORCID 0000-0001-7277-9170Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Bruce BeutleriD· 1 shared Evan Nair‐GilliD· 1 shared Hao WuiD· 1 shared Jessica Jia· 1 shared Luming CheniD· 1 shared Magdalena G. GrzemskaiD· 1 shared Michael Turner· 1 shared Nagesh PeddadaiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Bruce BeutlerORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintNov 5, 2025

The Structural Basis of Pacs1-Wdr37 Complex Assembly and Stability

Le Xiao, Magdalena G. Grzemska, Xiong Pi…·Evan Nair‐Gill

This paper presents the cryo-EM structure of the Pacs1-Wdr37 complex, revealing its assembly mechanism and stability, and identifies a mutation linked to neurodevelopmental syndrome.

1 citation

humancryo-EM

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