Author

Trevor J. Rutherford

MRC Laboratory of Molecular BiologyORCID 0000-0001-7294-1668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Gonzalo J. BeitiaiD· 1 shared Jan LöweiD· 1 shared Mariann BienziD· 1 shared Melissa V. R. GammonsiD· 1 shared Miha RenkoiD· 1 shared Nicolas L. JeaniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperCell Biology

Gonzalo J. BeitiaORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 26, 2025

Dishevelled drives Wnt-stimulated disassembly of primary cilia through a unique PDZ-mediated binding mode with Daple and Girdin

Miha Renko, Gonzalo J. Beitia, Trevor J. Rutherford…·Melissa V. R. Gammons

The study identifies a unique PDZ-mediated interaction between Dishevelled and Daple/Girdin-L that drives Wnt5a-induced primary cilia disassembly.

DOI 10.1101/2025.09.26.678488

humanbiophysical modeling

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedJun 8, 2020

FtsK in motion reveals its mechanism for double-stranded DNA translocation

Nicolas L. Jean, Trevor J. Rutherford, Jan Löwe

The paper determines the cryo-EM structure of FtsK's motor domain translocating DNA, revealing a mechanism involving conformational changes and spiral staircase interactions.

64 citationstop 3%

bacteria (other)experimental assay

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