Michael A. Quezada

This study identifies engineered histone variants that modulate chromatin structure and function, revealing sequence-to-function patterns and enabling the design of synthetic histones for specific chromatin states.

This study identifies the NLGN3-CSPG4-PIEZO1 axis as a regulator of glial precursor cell state and glioma proliferation through mechanosensitive signaling.

This study identifies functional GABAergic neuron-to-glioma synapses in diffuse midline gliomas that promote tumor proliferation and shows that drugs modulating GABAergic signaling affect glioma growth.